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通过使用生理学基础的药理动力学建模来评估载体介导的里法-林佐利德相互作用

Hoang Dat Nguyen1, Vinh Hoa Pham2, Richard M Hoglund3,4

  • 1Master of Science Program in Biopharmaceutical Sciences, Department of Biochemistry, Faculty of Pharmacy, Mahidol University, Bangkok, Thailand.

British journal of clinical pharmacology
|January 27, 2026
PubMed
概括

结合ATP的磁带亚家族B成员1 (ABCB1) 载体主要驱动着里法和线索立德之间的药物相互作用. 与标准剂量相比,高剂量的利法并不显著改变线索利德的暴露.

关键词:
药物 药物相互作用在线zolidlid是什么意思基于生理学的药物动力学模型.这就是为什么Rifampin是Rifampin.运输商 运输商 运输商 运输商

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