三重阴性乳腺癌和人工智能:目前的诊断模式,治疗预测,预后和挑战
Anupam Sharma1, Abhinav Sharma2, Priyancka Arora3
1Department of Physics, Guru Kashi University, Talwandi Sabo, Bathinda, Punjab, 151302, India.
Current pharmaceutical biotechnology
|January 27, 2026
概括
人工智能 (AI) 显著提高了三阴性乳腺癌 (TNBC) 诊断,预后和治疗预测. 进一步验证对于将AI整合到TNBC管理的精密瘤学中至关重要.
科学领域:
- 在瘤学瘤学.
- 医疗成像医学成像
- 人工智能的人工智能
背景情况:
- 三阴性乳腺癌 (TNBC) 是一种具有不良预后和有限治疗选择的侵袭性亚型.
- 人工智能 (AI),机器学习 (ML),深度学习 (DL) 和放射学在TNBC管理方面提供了有前途的进步.
- 当前的人工智能应用正在改善TNBC的诊断准确性,预后预测和治疗策略.
研究的目的:
- 审查人工智能,ML,DL和放射学在TNBC诊断,预后和治疗方面的最新进展.
- 通过整合各种数据类型来突出AI在开发个性化治疗策略中的作用.
- 讨论TNBC临床实践中AI实施的挑战和未来方向.
主要方法:
- 对TNBC应用的最新AI,ML,DL和放射学模型的审查.
- 使用成像 (乳房影像,超声波) 和组织病理学数据对人工智能驱动的诊断和预后模型进行分析.
- 探索AI与纳米技术和omics数据的整合,以实现个性化治疗和生存预测.
主要成果:
- 人工智能模型在TNBC诊断,亚型 (高达99.2%) 和预测新辅助化疗反应 (AUC高达0.96) 中表现出高准确度.
- 纵向放射学模型通过将超声波和临床数据整合起来,达到0.924 (训练) 和0.875 (测试) 的AUC.
- 人工智能衍生的免疫特征和瘤微环境特征显示出无疾病和整体生存的预后价值 (C指数0.65-0.76).
结论:
- 人工智能显著提高了TNBC的诊断和预后能力,提供了个性化的治疗计划.
- 人工智能与成像,奥米克和临床数据的整合有助于风险分层和治疗选择.
- 多中心验证和前性试验对于在TNBC精密瘤学中广泛采用AI的临床应用至关重要.
关键词:
三阴性乳腺癌是三阴性乳腺癌.人工智能的人工智能是人工智能.深度学习是一种深度学习.影像成像技术 影像成像技术机器学习是机器学习.预后 预后 预后无线电学 (radiomics) 是一种无线电学.预测治疗反应.更多相关视频
09:01Magnetic-, Acoustic-, and Optical-Triple-Responsive Microbubbles for Magnetic Hyperthermia and Pothotothermal Combination Cancer Therapy
Published on: May 22, 2020
3.5K
09:11Automation of the Micronucleus Assay Using Imaging Flow Cytometry and Artificial Intelligence
Published on: January 27, 2023
2.7K
相关概念视频
Cancer Therapies
10.1K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
10.1K
Targeted Cancer Therapies
8.9K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
There are several types of targeted therapies against...
8.9K
Intelligence
8.6K
The term "intelligence" is complex because it refers to both behavior and individuals, and its interpretation varies across cultures. European Americans tend to link intelligence with reasoning and cognitive skills, while in Kenya, it is tied to responsible participation in family and social life. In Uganda, intelligence is seen as the ability to know the right actions and carry them out effectively, while the Iatmul people of Papua New Guinea associate it with the capacity to remember...
8.6K
Predicting Molecular Geometry
45.7K
VSEPR Theory for Determination of Electron Pair Geometries
45.7K
Scalar and Vector Triple Products
4.4K
Two vectors can be multiplied using a scalar product or a vector product. The resultant of a scalar product is scalar, while with vector products, the resultant is a vector. These rules of the scalar or vector product between two vectors can be applied to multiple vectors to obtain meaningful combinations. The scalar triple product is the dot product of a vector with the cross product of two vectors.
The scalar triple product is the dot product of a vector with the cross product of two vectors....
The scalar triple product is the dot product of a vector with the cross product of two vectors....
4.4K
Measures of Intelligence
8.4K
Psychologists measure intelligence by using standardized tests that produce a score known as the intelligence quotient or IQ. To understand IQ tests, it's important to recognize the key principles behind their construction: validity, reliability, and standardization.
Validity refers to how well a test measures what it claims to measure. An intelligence test should accurately assess intelligence rather than another characteristic, like anxiety. Criterion validity is one way to evaluate this;...
Validity refers to how well a test measures what it claims to measure. An intelligence test should accurately assess intelligence rather than another characteristic, like anxiety. Criterion validity is one way to evaluate this;...
8.4K
