3D打印和纳米材料的进步为个性化药物输送提供了帮助
M Arjun Gokulan1, J Narayanan1
1Department of Pharmacology, SRM College of Pharmacy, Faculty of Medicine and Health Sciences, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu- 603 203, Tamil Nadu, India.
Current drug delivery
|January 27, 2026
概括
3D打印与纳米材料相结合,可以创建个性化的药物输送系统和植入物. 这项技术为向治疗和控制释放提供了先进的解决方案,改善了患者的治疗结果.
科学领域:
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
- 制药科学 制药科学
背景情况:
- 3D打印 (增材制造) 能够实现针对患者的药物输送系统和植入物.
- 纳米材料提供了增强的药物稳定性,有针对性的输送和受控释放能力.
研究的目的:
- 审查3D打印技术与纳米材料的集成,用于先进的药物输送和生物医学植入物.
- 突出这一跨学科领域的创新应用和未来方向.
主要方法:
- 讨论关键的3D打印技术:沉积建模 (FDM),立体石刻 (SLA),直接能量沉积 (DED) 和电.
- 检查材料的兼容性,包括聚合物,金属,陶和复合材料.
- 对纳米材料如树枝状体,脂质体,纳米颗粒,碳纳米管和外体的批判性审查.
主要成果:
- 3D打印可方便复杂的剂量形式,如多种药丸,胃浮动药片和分隔系统.
- 3D打印的药物释放植入物显示出局部癌症和传染病治疗具有延长释放和生物相容性的前景.
- 这些系统具有类似于人类组织的机械特性.
结论:
- 3D打印和纳米材料的融合正在彻底改变药物输送和可植入设备.
- 未来的进步包括智能材料,表面修饰的纳米粒子和人工智能,用于个性化,可持续的医疗解决方案.
- 克服扩展和监管障碍对于广泛采用至关重要.
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