创伤性下肢截肢的特征:医疗和社会并发症
Mark D Marino1, Sophia Izhar1, Heidi Israel1
1Orthopaedic Surgery, Saint Louis University School of Medicine, Saint Louis, USA.
Cureus
|January 27, 2026
概括
糖尿病和高血压等疾病增加了创伤性下肢截肢的风险. 创伤性脑损伤可能会降低截肢率,而酒精中毒与截肢可能性更高有关.
科学领域:
- 创伤外科 手术 创伤外科
- 整形外科手术 整形外科手术
- 公共卫生 公共卫生
背景情况:
- 创伤性下肢截肢是普遍存在的,但特定的风险因素仍未得到充分研究.
- 现有的研究集中在非创伤性截肢,忽视创伤作为一个重要的原因.
- 了解与创伤性截肢相关的并发症对于预防和管理至关重要.
研究的目的:
- 为了确定与创伤性下肢截肢率增加相关的医疗状况.
- 调查与非创伤性截肢相关的并发症是否也适用于创伤性病例.
- 探索创伤性脑损伤和物质使用对截肢结果的影响.
主要方法:
- 使用美国一级创伤中心 (2017-2022) 的计费记录进行了回顾性病例对照研究.
- 确定了63个创伤性下肢截肢病例和129个具有类似骨折的匹配对照.
- 使用皮尔森基平方测试来分析并发症和截肢率之间的关联.
主要成果:
- 糖尿病,高血压,骨髓炎,筋切割,酒精中毒和慢性病与更高的截肢率相关.
- 创伤性脑损伤与截肢可能性显著降低相关 (p=0.011).
- 酒精,大麻或阿片类药物/芬太尼尔中毒与高能量多创伤和机动车辆事故有关.
结论:
- 以前与非创伤性截肢相关的医学并发症也与创伤性下肢截肢有关.
- 创伤性脑损伤可能会对截肢产生保护作用.
- 酒精中毒和物质使用与截肢率增加和受伤严重程度有关.
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