减少但不均:孕产妇出血负担的全球演变及其未来轨迹
1Department of Gynecology, Pingdu People's Hospital, Qingdao, Shandong 266700, China.
Journal of perinatal medicine
|January 27, 2026
概括
从1990年到2021年,全球范围内孕产妇出血负担有所下降,但撒哈拉以南非洲的高率仍然存在. 有针对性的干预措施对于解决这些差异和减少孕产妇发病率和死亡率至关重要.
科学领域:
- 全球健康 全球健康
- 产科和妇科 产科和妇科
- 流行病学 流行病学
背景情况:
- 孕产妇出血是导致孕产妇发病和死亡的主要全球原因.
- 在孕产妇出血负担方面存在显著的区域差异.
研究的目的:
- 利用2021年全球疾病负担 (GBD) 数据,分析1990年至2021年母亲出血的全球和区域趋势.
- 检查发病率,死亡率和残疾调整寿命年 (DALYs) 的趋势,并预测未来的负担.
主要方法:
- 在204个国家和地区对孕产妇出血的发病率,死亡率和DALY进行分析.
- 关键指标的估计年度百分比变化 (EAPC) 的计算.
- 使用贝叶斯年龄-时期-队列模型预测未来趋势.
主要成果:
- 全球孕产妇出血发病率,DALY和死亡率在1990年至2021年期间显著下降.
- 发病率,DALY和死亡率的年龄标准化率显示大幅下降,最大的减少发生在东亚和南亚.
- 高发病率,DALY和死亡率仍然存在于社会人口指数较低的地区,特别是撒哈拉以南非洲中部和西部.
结论:
- 尽管全球减少了,但孕产妇出血负担的区域差异仍然很大.
- 低资源环境,特别是撒哈拉以南非洲地区,面临着不成比例的高负担.
- 在高负担地区,有针对性的干预措施至关重要,以进一步降低孕产妇发病率和死亡率.
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