裂手术中的预防性抗生素治疗-一个范围审查
Margareta Budner1,2, Marcelina Podleśna2,3, Aleksandra Domańska4
1Department of Jaw Orthopedics, Medical University of Lublin, 20-059 Lublin, Poland.
Dentistry journal
|January 27, 2026
概括
在裂唇和 palatal 手术中预防性抗生素的使用显示了广泛的变化. 短期抗生素策略似乎是有效的,强调了需要耐药意识的指导方针和进一步的研究.
科学领域:
- 面外科手术 面外科手术
- 传染性疾病传染性疾病.
- 药理学 药理学是指药理学的学科.
背景情况:
- 唇裂和/或裂手术是干净污染的手术,容易引起手术部位感染和裂.
- 目前的外科手术期间使用抗生素缺乏标准化,基于证据的建议.
- 抗菌素耐药性的增加需要在手术环境中合理的抗生素处方.
研究的目的:
- 系统地绘制有关裂口手术中预防性抗生素治疗的现有证据.
- 确定影响结果的相关外科手术期间措施.
- 为制定标准化,抵抗意识的指导方针提供信息.
主要方法:
- 按照Arksey和O'Malley框架进行系统的范围审查,并遵守PRISMA 2020指南.
- 搜索了PubMed,Mendeley和谷歌学者 (2015年1月至2025年2月) 相关的英语语言研究.
- 六位审查员的数据提取集中在研究特征,抗生素方案和结果上.
主要成果:
- 40项研究符合纳入标准,显示了抗生素选择,时间和持续时间的显著差异.
- 单剂量外科手术期间预防在某些情况下显示不劣于长期疗程.
- 口腔微生物群分析表明,裂口患者中存在耐药性病原体的殖民.
结论:
- 证据支持个性化的,短期的外科手术期间抗生素策略,而不是常规的长期治疗.
- 进一步进行高质量的随机对照试验和微生物学研究是必不可少的.
- 需要为裂口手术制定标准化,针对抗菌素耐药性的指导方针.
相关概念视频
The Scope of Physics
52.8K
Physics is concerned with the interactions of energy, matter, space, and time, in order to discover the underlying mechanisms that underpin all phenomena. The word "physics" comes from the Greek word "phúsis", which means nature. Physics seeks to comprehend the natural world around us at its most fundamental level. It emphasizes the use of quantitative laws to do this, which could be valuable in other fields that want to push the performance boundaries of present...
52.8K
Antibiotic Selection
59.9K
Overview
59.9K
Review and Preview
8.4K
In statistics, several tools are used to interpret the data. Measures of central tendency represent the characteristics of the data, such as mean, median, and mode. Additionally, measures of variance like standard deviation and range are used to find the spread of data from the mean. Relative standing measures the distance between data locations. Commonly used measures of relative standings are percentile, z score, and quartiles.
Percentiles are a type of fractile that partition data into...
Percentiles are a type of fractile that partition data into...
8.4K
Review and Preview
11.1K
Data are individual items of information obtained from a population or sample. Data may be classified as qualitative (categorical), quantitative continuous, or quantitative discrete. Because it is not practical to measure the entire population in a study, researchers use samples to represent the population. A random sample is a representative group from the population chosen by using a method that gives each individual in the population an equal chance of being included in the sample. Random...
11.1K
Development of Antibiotic Resistance
1.5K
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.5K
Gene Therapy
27.6K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
27.6K


