甘油三和社区居住的有代谢综合征的老年人的行走能力之间的关联
Chiraphat Kloypan1, Tichanon Promsrisuk2, Boonsita Suwannakul3
1Department of Pathology, School of Medicine, University of Phayao, Phayao 56000, Thailand.
Diseases (Basel, Switzerland)
|January 27, 2026
概括
老年人的代谢综合征 (MetS) 与较差的行走能力有关,功能测试,如五次坐立测试 (FTSST) 和定时起床 (TUG) 是关键指标,而不仅仅是代谢标志物.
科学领域:
- 老年学是一门学科.
- 心血管健康 心血管健康
- 运动生理学 运动生理学
背景情况:
- 代谢综合征 (MetS) 在老年人群中越来越令人担忧.
- 以前的研究表明,MetS与老年人身体功能下降之间存在联系.
- 代谢因素,生理反应和功能表现对MetS行走能力的具体贡献尚未完全理解.
研究的目的:
- 研究代谢综合征的组成部分,生理反应和功能表现与老年人行走能力之间的关联.
- 确定代谢生物标志物与功能和生理措施在预测行走能力方面的相对重要性.
- 评估功能测试和代谢标记器的歧视性表现,以识别减少的行走能力.
主要方法:
- 对116名60岁及以上的社区成年人进行横截面研究.
- 通过六分钟步行测试 (6MWT) 评估步行能力.
- 通过五次坐立测试 (FTSST),定时起站 (TUG) 和手握强度测量功能性表现;也记录了生理反应.
- 使用了等级回归和接收器运行特征 (ROC) 分析.
主要成果:
- 患有MetS的个体表现出明显更短的六分钟步行距离 (6MWD),更慢的FTSST和TUG时间,以及更高的呼吸障碍评级.
- 在完全调整后,缩血压变化 (ΔSBP) 和FTSST表现是6MWD的显著预测因素.
- 在FTSST和TUG中,低步行能力 (AUC>0.92) 具有很高的辨别能力,超过了甘油三水平 (AUC = 0.709).
结论:
- 老年人的行走能力与生理和功能性能的指标比单独的代谢生物标志物更强烈相关.
- FTSST和TUG是非常有效的工具,用于识别有减弱行走能力的老年人.
- 像甘油三等代谢标记物提供了补充信息,但与功能测试相比,它们对行走能力的预测能力不那么强大.
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