Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Autism Spectrum Disorder01:19

Autism Spectrum Disorder

1.1K
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
1.1K
Protein Glycosylation01:25

Protein Glycosylation

9.6K
Glycosylation, the most common post-translational modification for proteins, serves diverse functions. Adding sugars to proteins makes the proteins more resistant to proteolytic digestion. Glycosylated proteins can act as markers and receptors to promote cell-cell adhesion. Additionally, they have many essential quality control functions in the cell, such as correct protein folding and facilitating transport of misfolded proteins to the cytosol, which can be degraded.
Glycosylation occurs in...
9.6K
The Electromagnetic Spectrum02:37

The Electromagnetic Spectrum

65.1K
The electromagnetic spectrum consists of all the types of electromagnetic radiation arranged according to their frequency and wavelength. Each of the various colors of visible light has specific frequencies and wavelengths associated with them, and you can see that visible light makes up only a small portion of the electromagnetic spectrum. Because the technologies developed to work in various parts of the electromagnetic spectrum are different, for reasons of convenience and historical...
65.1K
The Electromagnetic Spectrum01:24

The Electromagnetic Spectrum

33.6K
Electromagnetic waves are categorized according to their wavelengths and frequencies, giving the electromagnetic spectrum. These waves are classified as radio, infrared, ultraviolet, etc. Radio waves refer to electromagnetic radiation with wavelengths ranging from millimeters to kilometers. Radio waves are commonly used for audio communications (i.e., radios) and typically result from an alternating current in the wires of a broadcast antenna. They cover a broad wavelength range and are used...
33.6K
IR Spectrum01:19

IR Spectrum

2.1K
When infrared (IR) radiation passes through a molecule, the bonds stretch or bend by absorbing the radiation. This absorption creates the molecule's absorption spectrum, which is the plot of its percentage transmittance versus wavenumber.
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0%...
2.1K
Binet's Contribution to Measures of Intelligence01:23

Binet's Contribution to Measures of Intelligence

1.7K
Alfred Binet, along with his student Théophile Simon, was tasked by the French Ministry of Education in 1904 to create a method for identifying students who struggled to learn through conventional classroom instruction. This initiative aimed to address overcrowding by placing such students in specialized schools. Binet and Simon developed an intelligence test comprising 30 tasks, ranging from simple commands, like touching one's nose or ear, to more complex tasks, such as drawing...
1.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Macrophage modulation accounts for the anti-inflammatory effect of Hypnea cervicornis agglutinin in rat arthritis induced by zymosan.

Glycoconjugate journal·2026
Same author

Crystal structure, glycan specificity, and induction of cellular stress by the legume lectin DmegA.

International journal of biological macromolecules·2026
Same author

Expression and characterization of an endo-β-1,6-galactanase from Arabidopsis thaliana.

The Biochemical journal·2025
Same author

Canavalia brasiliensis lectin attenuates diabetes endothelial dysfunction in rats: structural basis and implication of muscarinic/insulin receptors.

Biochemical and biophysical research communications·2025
Same author

Bridging Viral Glycobiology and Lectin Biotechnology for Antiviral and Diagnostic Strategies.

ACS bio & med chem Au·2025
Same author

Chimerolectins: Classification, structural architecture, and functional perspectives.

Protein science : a publication of the Protein Society·2025

相关实验视频

Updated: Jan 28, 2026

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
08:30

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

2.6K

改变膜糖化是否有助于自闭症谱系障碍的神经发育功能障碍?

Vinicius J S Osterne1, Messias V Oliveira1, Vanir R Pinto-Junior1

  • 1BioMol-Lab, Department of Biochemistry and Molecular Biology, Federal University of Ceará, Fortaleza 60440-970, Ceará, Brazil.

Membranes
|January 27, 2026
PubMed
概括

改变的糖基化影响自闭症谱系障碍 (ASD) 通过破坏神经元发育. 这篇综述统一了糖蛋白和糖脂缺陷,揭示了ASD突触病理的共同途径.

关键词:
葡萄糖合物 葡萄糖合物含有高曼诺斯的高曼诺斯含量脂质漂浮艇是什么意思 脂质漂浮艇是什么意思酸是酸的一种.突触性可塑性 突触性可塑性

更多相关视频

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

17.0K
A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder
08:17

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

Published on: April 12, 2018

11.1K

相关实验视频

Last Updated: Jan 28, 2026

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
08:30

Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests

Published on: September 6, 2024

2.6K
Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
09:13

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder

Published on: April 22, 2015

17.0K
A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder
08:17

A Semantic Priming Event-related Potential ERP Task to Study Lexico-semantic and Visuo-semantic Processing in Autism Spectrum Disorder

Published on: April 12, 2018

11.1K

科学领域:

  • 神经科学是一个神经科学.
  • 葡萄糖生物学 葡萄糖生物学
  • 发展生物学 发展生物学

背景情况:

  • 神经元发育取决于细胞表面的糖结合物作为生物信息代码.
  • 改变的糖基化在自闭症谱系障碍 (ASD) 的病理生理学中越来越被认可.
  • 大脑独特的甘氨酸特征易受家庭静止干扰,影响糖蛋白和糖脂质.

研究的目的:

  • 在ASD病理生理学中合成糖蛋白和糖脂的证据.
  • 为它们的病原性相互作用提出一个统一的框架.
  • 为了阐明多种不同的病因因素如何汇聚在受损的甘氨酸成熟.

主要方法:

  • 对ASD中膜糖结合物的现有文献的综述.
  • 检查关键葡萄糖蛋白 (如NCAM1,神经蛋白) 的缺陷及其与突触功能的联系.
  • 分析糖蛋白与化物丰富的脂质环境之间的功能合.

主要成果:

  • 像NCAM1和神经蛋白等糖蛋白的缺陷会损害突触信号传递,贩运和可塑性.
  • 这些糖蛋白缺陷在功能上与糖脂 (化物) 环境有关,这对膜平台至关重要.
  • 多种上游原因 (遗传,环境,表观遗传) 汇聚在受损的甘氨酸成熟上.

结论:

  • 葡萄糖蛋白和葡萄糖脂系统不是独立的,而是代表了ASD的共同途径.
  • 受损的糖甘成熟会损害膜信号平台,导致突触病理.
  • 这种统一的模型解释了各种自闭症病因如何导致类似的下游效应.