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相关概念视频

What is a Sensory System?01:31

What is a Sensory System?

101.0K
Sensory systems detect stimuli—such as light and sound waves—and transduce them into neural signals that can be interpreted by the nervous system. In addition to external stimuli detected by the senses, some sensory systems detect internal stimuli—such as the proprioceptors in muscles and tendons that send feedback about limb position.
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Repressible Operon: trp Operon01:21

Repressible Operon: trp Operon

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The trp operon in Escherichia coli exemplifies a repressible operon. It regulates the synthesis of tryptophan through repressor-mediated transcriptional control and attenuation. This dual regulatory mechanism ensures tryptophan biosynthesis occurs only when needed, conserving cellular resources.Structure of the trp OperonThe trp operon consists of five structural genes (trpE, trpD, trpC, trpB, and trpA) that encode enzymes for tryptophan biosynthesis. These genes are transcribed as a single...
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lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

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In humans, more than 80% of the genome gets transcribed. However, only around 2% of the genome codes for proteins. The remaining part produces non-coding RNAs which includes ribosomal RNAs, transfer RNAs, telomerase RNAs, and regulatory RNAs, among other types. A large number of regulatory non-coding RNAs have been classified into two groups depending upon their length – small non-coding RNAs, such as microRNA, which are less than 200 nucleotides in length, and long non-coding RNA...
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lncRNA - Long Non-coding RNAs02:39

lncRNA - Long Non-coding RNAs

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Nursing Code of Ethics01:29

Nursing Code of Ethics

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The Nursing Code of Ethics sets the ethical benchmark for the profession, and guides nurses in ethical analysis and decision making at the societal, organizational, and clinical levels. The code encompasses showing compassion and respect for the patient, their families, and communities in all circumstances while committing to providing patient-centered care. In addition, the code states that nurses must advocate for the patient by defending a cause or recommendation to protect their rights,...
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Ion Channels01:19

Ion Channels

91.4K
The movement of ions like sodium, potassium, and calcium into and out of the cell is essential to maintain the electrochemical gradient in living cells. The ion channels—a class of membrane transport proteins—help maintain this ionic gradient for the smooth functioning of physiological activities such as maintaining cell size and volume, conducting nerve impulses, and gas and nutrient exchange.
Ion channels are specialized integral membrane proteins on the plasma membrane that allow...
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相关实验视频

Updated: Jan 28, 2026

Identification of Specific Sensory Neuron Populations for Study of Expressed Ion Channels
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Identification of Specific Sensory Neuron Populations for Study of Expressed Ion Channels

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从感官编码到生理学的TRP道.

Muhammad Atif1,2, Youngseok Lee1,2

  • 1Department of Bio and Fermentation Convergence Technology, Kookmin University, Seoul 02707, Republic of Korea.

Metabolites
|January 27, 2026
PubMed
概括

瞬态受体潜能 (TRP) 道是参与检测口味,气味和内部状态的多功能传感器. 这些通道在化学感应中起着至关重要的作用,影响行为和生理调节.

科学领域:

  • 神经科学是一个神经科学.
  • 分子生物学分子生物学
  • 感官生物学 感官生物学

背景情况:

  • 感官系统检测适应性反应的线索,化学感觉对于养,交配和避免毒素至关重要.
  • 暂时受体潜在 (TRP) 通道,传统上与其他感官联系在一起,越来越多地被认为是它们的化学传感作用.
  • 在种群中发现了TRP通道,证明了化学检测中的进化保护和功能多功能性.

研究的目的:

  • 综合当前关于TRP通道化学传感功能的知识.
  • 探索TRP通道在味觉,嗅觉,内部状态感知和中央电路调制中的作用.
  • 为了提供一个比较框架,使用Drosophila melanogaster和哺乳动物系统.

主要方法:

  • 文献综述和现有关于TRP通道功能在化学传感中的研究的综合.
  • 在 *Drosophila melanogaster* 和哺乳动物系统中对TRP通道作用的比较分析.
  • 检查TRP通道作为受体通路内的多模式传感器,信号放大器和调节器.

主要成果:

  • TRP通道检测味道,气味和内部化学状态,超越它们的传统感官作用.
  • TRP通道作为已建立的感觉通路中的集成组件,充当多模式传感器和信号放大器.
关键词:
这种植物是Drosophila melanogaster.化学感应是一种化学感应.多感应集成的多感应集成暂时受体潜力 (TRP) 道的道.

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Cell-based Calcium Assay for Medium to High Throughput Screening of TRP Channel Functions using FlexStation 3
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Quadruple Immunostaining of the Olfactory Bulb for Visualization of Olfactory Sensory Axon Molecular Identity Codes
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Quadruple Immunostaining of the Olfactory Bulb for Visualization of Olfactory Sensory Axon Molecular Identity Codes

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相关实验视频

Last Updated: Jan 28, 2026

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11:34

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Cell-based Calcium Assay for Medium to High Throughput Screening of TRP Channel Functions using FlexStation 3
07:26

Cell-based Calcium Assay for Medium to High Throughput Screening of TRP Channel Functions using FlexStation 3

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Quadruple Immunostaining of the Olfactory Bulb for Visualization of Olfactory Sensory Axon Molecular Identity Codes
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Quadruple Immunostaining of the Olfactory Bulb for Visualization of Olfactory Sensory Axon Molecular Identity Codes

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  • 有证据支持TRP通道参与协调行为与内部生理状态.
  • 结论:

    • TRP通道是化学感应的组成部分,作为多功能,集成的传感器而不是独立的受体.
    • 了解TRP通道功能,可以深入了解协调行为与内部状态和平稳调节的关系.
    • TRP通道代表了化学感知障碍和代谢疾病的潜在治疗点.