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相关概念视频

Curing of Concrete01:20

Curing of Concrete

366
The hydration of cement takes place within the water-filled capillary pores. However, environmental elements can disrupt this process by evaporating water from the concrete surfaces. Sealed concrete with a water-cement ratio below 0.5 experiences self-desiccation, leading to water loss. The water loss in concrete is mitigated by curing. This technique involves keeping the concrete saturated to maintain the necessary temperature and moisture conditions, to optimally fill the spaces in the cement...
366
Curing Methods01:26

Curing Methods

292
Concrete members with a small surface-to-volume ratio are cured by oiling and moistening the forms before casting the concrete member. These forms can be left in place for a prolonged period to prevent moisture loss, and can be wetted if made of a material suitable for wetting. If the forms are removed early, the concrete member is moistened and covered with polythene sheets to maintain moisture. For large horizontal concrete surfaces exposed to dry weather, a temporary covering is suspended...
292
Accelerated Curing of Concrete01:25

Accelerated Curing of Concrete

471
Accelerating concrete curing is achieved by applying heat and additional moisture. This process accelerates the hydration of the cement, resulting in an earlier strength gain in the concrete. Steam curing is a method wherein the concrete products are either transported through a chamber on a conveyor belt or encased in plastic, allowing steam at atmospheric pressure to circulate freely around them. This process begins with a phase of moist curing that typically lasts between 3 to 5 hours, after...
471
Kinetic Energy00:23

Kinetic Energy

43.4K
Kinetic energy is the ability of an object in motion to do work or enact change. It can take on many forms. For instance, water flowing down a waterfall has kinetic energy. In biological systems, particles of light travel and are absorbed by plants to create chemical energy. Animals consume the chemical energy and give off molecules that carry their scent through the air. They also generate kinetic energy when they run away from predators. Entire systems also possess kinetic energy, like the...
43.4K
Enzyme Kinetics01:19

Enzyme Kinetics

104.0K
Enzymes speed up reactions by lowering the activation energy of the reactants. The speed at which the enzyme turns reactants into products is called the rate of reaction. Several factors impact the rate of reaction, including the number of available reactants. Enzyme kinetics is the study of how an enzyme changes the rate of a reaction.
Scientists typically study enzyme kinetics with a fixed amount of enzyme in the controlled environment of a test tube. When more reactant, or substrate, is...
104.0K
Kinetic Molecular Theory: Molecular Velocities, Temperature, and Kinetic Energy03:07

Kinetic Molecular Theory: Molecular Velocities, Temperature, and Kinetic Energy

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The kinetic molecular theory qualitatively explains the behaviors described by the various gas laws. The postulates of this theory may be applied in a more quantitative fashion to derive these individual laws.
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3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds
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照片交叉链接混合水凝用于高保真性直接写入3D打印:风病学,治疗动力学和生物支架制造.

Riley Rohauer1, Kory Schimmelpfennig2, Perrin Woods3

  • 1Department of Biomedical Engineering, Rochester Institute of Technology, Rochester, NY 14623, USA.

Journal of functional biomaterials
|January 27, 2026
PubMed
概括

这项研究开发了使用酸盐,碳甲基纤维素和聚乙烯甘二烯酸盐 (PEGDA) 的新型混合水凝,用于3D生物打印. 这些材料表现出更好的可打印性和可调节的刚性,使得复杂的组织支架可以创建.

关键词:
紫外线交叉连接的UV交叉连接直接写入的3D生物打印.发光线的融合方式混合水凝是一种混合水凝.可调节的属性.

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科学领域:

  • 生物材料科学 生物材料科学
  • 聚合物化学 聚合物化学
  • 组织工程是组织工程.

背景情况:

  • 像酸盐和甲基纤维素 (CMC) 这样的天然聚合物具有生物相容性,但往往缺乏机械强度和精确的可用于组织工程的打印能力.
  • 合成聚合物,如聚乙烯甘) 二烯酸盐 (PEGDA) 可以增强机械性能和交叉连接控制.
  • 混合水凝结合了天然和合成成分,旨在在先进的应用中利用这两种材料的优势.

研究的目的:

  • 描述由酸盐,CMC和不同度的PEGDA组成的混合液体.
  • 通过使用直接写入 (DW) 3D生物打印来评估这些混合水凝的可打印性,固化动力学和机械性能.
  • 评估这些材料在为组织类型的高分辨率支架制造方面的潜力.

主要方法:

  • 混合水凝的制备,含有4%的酸盐,4%的CMC和0,4.5%,6.5%或10%的PEGDA.
  • 使用旋转类风学进行粗热态行为和丝融合测试以进行可打印和扩散的表征.
  • 通过光差扫描热量计 (DSC) 和光雷奥学评估固化动力学.
  • 使用DW 3D生物打印机评估机械性能 (复杂模量,G*) 和脚手架制造.

主要成果:

  • 混合水凝表现出可调节的硬度 (620-4600Pa),PEGDA含量增加,适用于各种组织类型.
  • 在现场的紫外线照射显著改善了印刷结构的形状保真性,并减少了丝扩散.
  • 卡马尔模型准确地描述了固化动力学,光雷奥学证实了紫外线暴露时增加的刚性.
  • 使用优化的混合水凝成功打印了具有1x1毫米孔的高分辨率10层支架.

结论:

  • 含有PEGDA的混合水凝非常适合用于高分辨率的直接写入3D生物打印.
  • 可调节的机械性能和增强的可打印性使这些材料成为开发可定制组织类型的有希望的材料.
  • 现场紫外线交叉连接是实现印刷脚手架精确结构保真的关键因素.