使用树脂修饰的生命脉治疗的临床和放射性结果与传统的酸基材料相比:系统性审查和元分析
Alberto Cabrera-Fernández1, Laura Dominguez-Dominguez1, Antonio Pérez-Pérez2
1Department of Stomatology, Endodontic Section, School of Dentistry, University of Sevilla, 41009 Sevilla, Spain.
Journal of functional biomaterials
|January 27, 2026
概括
树脂改性酸盐基材料 (RM-CSMs) 在生命性纸治疗中显示出与传统材料相似的短期成功. 然而,与非树脂改性材料相比,RM-CSM在长期修复和牙形成方面存在局限性.
科学领域:
- 牙周内科医院 牙周内科医院 牙周内科医院
- 牙科材料科学 牙科材料科学
- 恢复性牙科 恢复性牙科
背景情况:
- 生命脉治疗 (VPT) 是根管治疗的替代方案,用于治疗深层.
- 树脂改性酸盐基材料 (RM-CSMs) 提供了处理优势,但它们的生物学有效性仍在争论中.
研究的目的:
- 系统地审查和元分析使用RM-CSM与传统非树脂改性酸盐基材料 (NRM-CSM) 的VPT的临床和放射性结果.
主要方法:
- 按照PRISMA指南进行系统审查.
- 在 Medline,Embase,Scopus,Web of Science 搜索到 2025 年 10 月.
- 包括间接/直接脉封闭或脉切除的随机临床试验.
- 对 TheraCal LC 的元分析;评估了偏差风险和证据的确定性.
主要成果:
- 在RM-CSMs和NRM-CSMs之间短期 (90/180天) 临床放射学成功没有显著差异.
- 一个不显著的趋势有利于NRM-CSMs在360天.
- 在360天后观察到TheraCal LC的明显较低的牙桥形成.
结论:
- RM-CSM提供了可比的短期VPT成功,但具有长期的生物限制.
- 对于可预测的牙生成和最大的生物活性,NRM-CSM是首选的.
- 需要进一步研究RM-CSMs的长期修复性结果.
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