纳米粒子监管的演变:对研究趋势和历史并行 (2015-2025) 的元分析
Sung-Kwang Shin1, Niti Sharma2, Seong Soo A An2
1Department of Global Culture & Contents, Hankuk University of Foreign Studies, Dongdaemun-gu, Seoul 02450, Republic of Korea.
Nanomaterials (Basel, Switzerland)
|January 27, 2026
概括
纳米粒子调节研究显示了一个成熟的,多学科领域. 未来的治理需要适应性,数据化和协调的创新和安全框架.
科学领域:
- 纳米技术治理 纳米技术治理
- 监管科学 监管科学
- 公共卫生政策 公共卫生政策
背景情况:
- 纳米技术的快速发展需要不断发展的监管框架.
- 与辐射监管的历史并行提供了纳米技术治理的见解.
- 了解纳米粒子研究的主题演变对于有效监督至关重要.
研究的目的:
- 分析纳米粒子调节研究的框架演变和专题结构.
- 评估管理快速发展的纳米技术当前面临的挑战.
- 用历史辐射监管平行来将新兴的监管策略置于背景.
主要方法:
- 9095篇PubMed索引文章的文本挖掘和主题建模 (2015-2025年).
- 使用TF-IDF和非负矩阵分解 (NMF) 来提取主题.
- 使用UMass分数和定性可解释性评估主题连贯性.
主要成果:
- 确定了六个关键研究主题:能源/传感器,金属氧化物毒性,银纳米颗粒,癌症纳米疗法,药物/mRNA输送.
- 2019年后的出版物显著增长,主要是跨学科期刊.
- 越来越多地将监管方面 (安全,环境影响) 纳入生物医学研究.
结论:
- 纳米粒子调节是一个动态的,多学科领域.
- 优先考虑适应性,基于数据的,国际协调的框架.
- 与人类和环境安全保证平衡创新支持.
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