上转化纳米粒子的制备方法及其生物应用
1School of Medicine and Health, Yancheng Polytechnic College, Yancheng 224005, China.
Nanomaterials (Basel, Switzerland)
|January 27, 2026
概括
向上转换纳米粒子 (UCNPs) 为先进的生物医学应用提供了独特的特性,如深层组织成像和向药物输送. 它们融入智能治疗系统有望实现个性化医疗,但生产和安全方面的挑战仍然存在.
科学领域:
- 纳米技术纳米技术
- 生物医学工程 生物医学工程
- 材料科学 材料科学 材料科学
背景情况:
- 下一代治疗设备需要智能,集成系统,合并多种功能.
- 上转化纳米粒子 (UCNPs) 具有独特的物理化学特性,使其具有多功能特性.
研究的目的:
- 审查最近在生物医学应用UCNP的设计和功能化方面的进展.
- 阐明UCNP在开发综合诊断和治疗平台方面的作用.
- 探索UCNP在智能响应性治疗系统和个性化医学的潜力.
主要方法:
- 系统审查关于UCNP设计和功能化的文献.
- 分析UCNP属性,包括近红外激发,深层组织透,低自发光和可调的多色发射.
- 评估UCNP在深层组织成像,向药物输送和光动力学治疗中的应用.
主要成果:
- 精细的制备方法为生物医学使用解锁了UCNP的新功能.
- UCNPs在深层组织成像,向药物输送和光动力学疗法方面显示出巨大的潜力.
- 统一的网络诊断平台促进了综合诊断和治疗平台的发展.
结论:
- UCNP是智能,响应性治疗系统和个性化医学的关键组成部分.
- 解决大规模生产,生物安全和体内机制方面的挑战对于临床转化至关重要.
- 未来的跨学科融合将增强基于UCNP的医疗创新.
相关概念视频
Applications Of NMR In Biology
4.5K
Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
4.5K
Biological Methods for Microbial Control
878
Biological agents offer an effective means of controlling microbial growth by leveraging natural processes like predation, competition, and the secretion of antimicrobial substances.Predatory bacteria such as Bdellovibrio species target and kill pathogens like Salmonella and E. coli. They are widely used in poultry farms to control infections. Myxococcus species help combat plant-pathogenic fungi. These naturally occurring predators serve as eco-friendly alternatives to chemical pesticides and...
878
What is Conservation Biology?
24.3K
Conservation biology is a scientific field that focuses on the preservation of biodiversity in order to protect ecosystems while meeting the needs of the human population. Humans require properly functioning ecosystems to maintain our supply of natural resources, including food, medicines, and building materials.
24.3K
Biological Effects of Radiation
17.8K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
17.8K
Synthetic Biology
5.6K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
Golden rice
Golden rice is a genetically modified...
5.6K
Biological Causes of Schizophrenia
572
Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin...
572


