肠上皮质AhR删除通过脂质和氨基酸代谢重编程加剧DSS诱导的大肠炎:综合代谢-转录组证据

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Yuanling Zhang1, Fengda Liu2, Chao Xu1

  • 1Department of General Surgery, Chongqing General Hospital, Chongqing University, Chongqing, China.

Inflammation research : official journal of the European Histamine Research Society ... [et al.]
|January 27, 2026
PubMed
概括

阿里碳水化合物受体 (AhR) 信号影响炎症性肠病 (IBD) 通过调节肠上皮细胞代谢. 在肠道细胞中删除AhR会破坏脂质和氨基酸代谢,在IBD模型中恶化炎症和屏障功能障碍.

关键词:
阿里碳水化合物受体是什么?炎症性肠病是一种炎症性肠病.肠道上皮质屏障 肠道上皮质屏障代谢过程中的代谢.

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