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Updated: Jan 28, 2026

Long-term Live-cell Imaging to Assess Cell Fate in Response to Paclitaxel
08:29

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作为OATP1B型运输机的光探针的帕克利塔克塞尔的太平洋蓝色衍生品

Mahesh R Nepal1, Yue Xu1, Yan Jin1

  • 1Division of Pharmaceutics and Pharmacology, The Ohio State University, Columbus, Ohio, USA.

Clinical and translational science
|January 27, 2026
PubMed
概括

新的光帕克利塔塞尔 (Taxol) 衍生物,PB-taxoids,有效地模仿帕克利塔塞尔的运输和神经毒性. 这些探针有助于研究与OATP载体相关的药物相互作用和毒性.

关键词:
这是一个OATP1B的OATP1B.太平洋的蓝色是太平洋的蓝色.毒品运输商 毒品运输商帕克利塔克塞尔 (paclitaxel) 的使用情况

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