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Updated: Jan 29, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
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产生IgA的B细胞通过Granzyme B在脏中发挥调节功能

Laureline Berthelot1, Nicolas Degauque1, Laura Cappelier1

  • 1Inserm, Nantes Université, CHU de Nantes, Center for Research in Transplantation and Translational Immunology CR2TI, UMR 1064, ITUN, Nantes, France.

Kidney360
|January 27, 2026
PubMed
概括

耐受性移植接受者显示,IgA分泌和大酶B表达调节性B细胞 (Bregs) 之间存在强烈联系. 这些IgA+Bregs增强了抑制性质,对移植耐受性至关重要.

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