胎儿RFOF模仿CoA:心脏输出和左心脏形态参数的预测和差值
Qin Lin1,2, Kexuan Liu1,2, Pan Yang1,2
1Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
冗余的卵巢孔 (RFOF) 可以在超声波上模仿大动脉 (CoA) 的缩. 新的回声心脏学参数,如FOFd/LAd比率和大动脉门角,有助于区分胎儿的RFOF与CoA.
科学领域:
- 胎儿心脏病学 胎儿心脏病学
- 诊断成像 诊断成像 诊断成像
- 遗传性心脏病是一种先天性心脏病.
背景情况:
- 冗余的卵巢孔 (RFOF) 可以呈现类似的心声回声检查结果,以大动脉 (CoA).
- 现有的方法缺乏全面的指标,可以在产前可靠地区分RFOF和CoA.
- 血液动力学和左心形态参数对于准确的产前诊断至关重要.
研究的目的:
- 为了研究RFOF对心脏输出的影响.
- 评估新的左心脏参数,以区分RFOF与CoA.
- 建立特定的标记来区分这两种胎儿心脏病.
主要方法:
- 对怀疑COA和对照的胎儿进行前性诊断队列研究.
- 包括心脏输出和新参数 (RCO/LCO,FOFd/LAd,大动脉弧角,LIOA) 在内的综合回声心脏学.
- 接收器运行特征 (ROC) 曲线分析,以评估指标的预测值.
主要成果:
- 在RFOF病例中,FOFd/LAd比率显示了最高的AUC,其次是RCO/LCO.
- 在CoA病例中,大动脉峡/大动脉管径 (Aoi/DA) 和大动脉角的AUC最高.
- 对于FOFd/LAd和RCO/LCO的特定值表示RFOF,而大动脉弧角和Aoi/DA则表明CoA.
结论:
- FOFd/LAd>0.65是RFOF的特定标志物,而RCO/LCO>1.60提供了支持性证据.
- 大动脉弧角>75.84°和Aoi/DA<0.75强烈表明CoA.
- 联合使用FOFd/LAd,大动脉弧角和LIOA可以改善RFOF和CoA之间的差异化.
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