在患有社会焦虑障碍的患者中进行代谢和减肥手术,一项匹配的队列研究
Jesper Christiansen1, Erik Näslund2, Henrik Larsson3,4
1Department of Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
PloS one
|January 27, 2026
概括
代谢和减肥手术 (MBS) 对患有社会焦虑障碍的严重肥胖患者是安全的. 虽然存在自我伤害等风险,但MBS提供了类似的减肥和心血管益处,改善了生活质量.
科学领域:
- 代谢和减肥手术的代谢和减肥手术.
- 精神病体医学是一种精神病体医学.
- 公共卫生 公共卫生
背景情况:
- 社会焦虑障碍 (SAD) 在寻求代谢和减肥手术 (MBS) 的患者中很普遍.
- 肥胖与SAD相结合可能会增加MBS后不良结果的风险.
- 了解这些风险对于患者管理至关重要.
研究的目的:
- 调查中度至严重的社会焦虑障碍与初级MBS后的结果之间的关联.
- 为了比较术后并发症,自我伤害,药物滥用,生活质量,体重减轻和心血管事件在患有和没有SAD的患者之间.
主要方法:
- 在瑞典 (2007-2019) 进行了全国范围的,基于注册的,匹配的队列研究.
- 通过使用倾向分数,将586名中度至重度SAD患者与5791名没有SAD的对照进行了匹配.
- 平均随访时间为6.9年.
主要成果:
- 患有SAD的患者患有非严重的术后并发症 (OR 1.59),自我伤害 (HR 2.44) 和酒精/药物滥用 (HR 2.41) 的风险增加.
- 在SAD组中,在手术前和手术后报告了与心理健康相关的生活质量较低.
- 在2年后观察到类似的体重减轻 (32.8%对32.6%) 和相似的心血管事件风险.
结论:
- 在中度至重度SAD患者中,MBS对严重肥胖的治疗是安全有效的.
- 对于这些患者,建议加强术前和术后的支持.
- 对于患有SAD患者来说,MBS从基线改善了生活质量.
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