微信小程序对代谢功能障碍相关的脂肪肝疾病的治疗效果:随机对照试验
Chao Sun1, Guangyu Chen2, Cuicui Shi1
1Center for Fatty Liver Disease, Department of Gastroenterology, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, 1665 Kong Jiang Road, Shanghai, 200092, China, 86 02125077340.
使用微信小程序进行的数字生活方式干预有效促进了代谢功能障碍相关脂肪肝病 (MAFLD) 患者的减肥和减少肝脂肪. 这种方法为中国的MAFLD管理提供了可扩展,低成本的解决方案.
科学领域:
- 与代谢功能障碍相关的脂肪肝疾病 (MAFLD)
- 数字健康干预措施 数字健康干预措施
- 改变生活方式改变生活方式
背景情况:
- 与代谢功能障碍相关的脂肪肝疾病 (MAFLD) 的管理需要减肥,这对患者来说是具有挑战性的.
- 对于中国的MAFLD来说,有很大需要量身定制的数字生活方式干预措施.
研究的目的:
- 评估基于微信小程序的生活方式干预对超重或肥胖的MAFLD患者减肥和肝肥胖症的影响.
主要方法:
- 一项前性随机对照试验招募了患有MAFLD的超重/肥胖成年人.
- 参与者被分配到微信小程序干预 (个性化饮食/运动,监测) 或标准护理.
- 结果,包括体重和肝脏参数,在基线和6个月后进行评估.
主要成果:
- 与对照组相比,干预组的体重减轻率≥5%和≥10%显著更高.
- 干预组中较大比例的干预组在控制减弱参数 (CAP) 中实现了≥10%的减少或正常化.
- 干预组在肝酶,代谢参数和FibroScan-aspartate aminotransferase评分方面表现出显著的改善.
结论:
- 一个微信小程序干预是有效的减肥和改善肝硬化和代谢参数在MAFLD患者.
- 这种可扩展,低成本的数字化方法解决了中国MAFLD管理的关键差距.
- 需要进一步的研究来证实这些发现并评估长期可持续性.
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