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Updated: Jan 29, 2026

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自我报告的疼痛敏感性在极度早产的成年人与期满的对照相比:一个匹配的队列研究
Julie Vestavik Berge1, Silje Nesthus1, Merete Røineland Benestad2
1Department of Paediatric and Adolescent Medicine, Haukeland University Hospital, Bergen, Norway.
Early human development
|January 27, 2026
概括
极度早产 (EP) 出生的年轻人与27岁出生的同龄人相比,在疼痛敏感度或药物使用方面没有差异. 新生儿疼痛手术在EP组中没有影响以后的疼痛敏感性.
科学领域:
- 新生儿护理的结果.
- 发育儿科 发育儿科
- 治疗疼痛的药物 治疗疼痛的药物
背景情况:
- 极度早产 (EP) 出生的个体可能会经历疼痛敏感度的改变.
- 在EP患者中,新生儿疼痛暴露的长期影响需要进一步研究.
研究的目的:
- 为了比较自我报告的疼痛敏感性和疼痛药物的使用,在成年人出生EP对比到期的对照.
- 评估EP组中新生儿疼痛手术和成人疼痛敏感性之间的关联.
主要方法:
- 基于人口的队列研究,在27岁时进行第三次随访.
- 参与者包括出生于EP的个人 (妊娠年龄≤28周) 和匹配的满期出生对照.
- 使用疼痛敏感性问卷 (PSQ) 评估疼痛敏感性;药物使用和新生儿手术也被记录.
主要成果:
- 没有显著的差异在PSQ分数 (总,中等,轻微) 之间的EP-born成人和终身对照.
- 在两组之间观察到类似的止痛药使用率.
- 在新生儿疼痛手术数量与27岁时疼痛敏感度之间没有发现任何关联.
结论:
- 自我报告的疼痛敏感性和止痛药的使用在出生于EP的成年人和27岁的出生于EP的同龄人之间是可比的.
- 在这个队列中,新生儿疼痛暴露似乎没有影响长期疼痛敏感性.
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