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Updated: Jan 29, 2026

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通过MNRR1进行转录激活是通过招募p300来实现的,并且可以通过最小的来诱导

Neeraja Purandare1, Vignesh Pasupathi1, Deepesh Padhan1

  • 1Center for Molecular Medicine and Genetics, United States.

Mitochondrion
|January 27, 2026
PubMed
概括

线粒体核逆行调节剂1 (MNRR1) 通过与RBPJk和p300相互作用来增强细胞应激反应,以调节基因转录. 来自MNRR1的激活线粒体通路,为MELAS提供治疗潜力.

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