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Updated: Jan 29, 2026

Whole Mount Immunofluorescent Staining of the Neonatal Mouse Retina to Investigate Angiogenesis In vivo
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Published on: July 9, 2013

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对新生小鼠视网膜增殖内皮细胞中VEGF介导信号通路的抑制作用的可视化

Akane Morita1, Kasumi Miyanaga1, Tsutomu Nakahara1

  • 1Department of Molecular Pharmacology, Kitasato University School of Pharmaceutical Sciences, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.

Microvascular research
|January 27, 2026
PubMed
概括

血管内皮生长因子 (VEGF) 在视网膜内皮细胞中激活mTORC1通路. 抑制VEGFR会破坏这种途径,导致内皮细胞退化,这表明PS6监测可以评估VEGF反应.

关键词:
血管新生的产生.内皮细胞是内皮细胞.拉帕素复合物的哺乳动物点1核糖体蛋白质S6 核糖体蛋白质S6血管内皮生长因子 血管内皮生长因子

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