在过度饮酒的中国老年男性中预防低骨质量的成本效益分析:一项建模研究
Xihan Lin1, Jinyu Liu2, Lin Wang1
1Department of Pharmacy, Huazhong University of Science and Technology Tongji Medical College Union Hospital, Wuhan, Hubei, China.
BMJ open
|January 27, 2026
概括
对过度饮酒的中国老年男性来说,查和抗骨质疏松症药物是具有成本效益的. 早期干预可以改善骨健康,并减少与低骨质量相关的经济负担.
科学领域:
- 老年学是一门学科.
- 公共卫生 公共卫生
- 药物经济学 药物经济学
背景情况:
- 低骨质量在中国造成了严重的健康负担,特别是影响过度饮酒的老年男性.
- 这些人往往被诊断不足,并没有充分治疗骨健康问题.
研究的目的:
- 对过度饮酒的中国老年男性进行查和抗骨质疏松药物预防低骨质量的经济评估.
- 评估不同预防策略的成本效益.
主要方法:
- 在经济评估中使用了患者级别的马尔科夫模型.
- 这项研究包括60岁以上的中国男性,他们过度饮酒.
- 干预措施包括查和抗骨质疏松药物,考虑骨质疏松症和骨质疏松症的资格.
主要成果:
- 从医疗保健的角度来看,预防策略对于70岁以上的男性来说是具有成本效益的 (骨质疏松症的ICER为28403美元/QALY,骨质疏松症的ICER为24560美元/QALY).
- 对60岁以上有风险因素的男性来说,查是具有成本效益的. 德诺苏马布在药物选择中显示出潜在的主导地位.
- 从社会角度来看,在60岁以上的男性中预防骨质疏松是具有成本效益的 (ICER为36,524美元/QALY).
结论:
- 预防策略,包括查和药物治疗,对于过度饮酒的中国老年男性来说是具有成本效益的.
- 早期查启动对于改善骨健康和减轻低骨质量的人文和经济负担至关重要.
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