克里佩尔-费尔综合征表现为儿童患者的后部循环中风
Xing-Chuan Li1, Song Wang2, Xiao-Yan Liu3
1Department of Pediatrics, Lanzhou University Second Hospital, Lanzhou, China 18294456578@139.com.
BMJ case reports
|January 27, 2026
概括
克里佩尔-费尔综合征 (KFS) 是一种罕见的椎融合障碍,即使没有短子,也可能导致严重的后部循环中风. 早期成像和多学科护理对于诊断和治疗至关重要.
科学领域:
- 神经学 神经学
- 遗传学 是一个遗传学.
- 儿科 儿科 儿科
背景情况:
- 克里佩尔-费尔综合征 (KFS) 是一种由椎结合定义的先天性疾病.
- KFS通常表现为具有特征的短子,但也会出现不典型的表现.
研究的目的:
- 报告一个Klippel-Feil综合征的病例,呈现为青少年的后部循环中风.
- 突出在没有典型表型的中风患者中识别KFS的重要性.
主要方法:
- 一个早期青少年患有KFS和后部循环中风的案例报告.
- 诊断成像包括MRI和MRA,以评估骨和血管异常.
- 临床评估神经系统缺陷和对治疗的反应.
主要成果:
- 患者在部运动后出现了急性神经缺陷 (头,吐,半)
- 图像检测显示KFS具有椎形异常和严重的脊椎关动脉狭窄/闭塞.
- 诊断出小脑和小脑的缺血性心脏病发作;患者缺乏典型的短现象型.
- 通过抗血小板治疗,抗凝血和康复,可以实现显著的神经系统改善.
结论:
- 克里佩尔-费尔综合征可以表现为危及生命的后部循环中风,即使没有经典的身体特征.
- 早期诊断成像对于识别KFS相关的血管并发症至关重要.
- 对于管理KFS和相关的脑血管事件,一个多学科的方法是必不可少的.
相关概念视频
Coronary Circulation
7.1K
The heart, an organ critical to survival, gets nourishment not from the blood it pumps but from a separate circulation system known as coronary circulation. This is the shortest circulation in the body and is responsible for supplying the heart with the nutrients it needs to function effectively.
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
Coronary circulation begins at the base of the aorta, where two main arteries arise—the left and right coronary arteries. These arteries encircle the heart in the coronary sulcus and supply the...
7.1K
Fetal Circulation
2.8K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
2.8K
Overview of Pulmonary Circulation
3.0K
The pulmonary circulation is a vital system in our body that acts as a bridge between the respiratory and cardiovascular systems. It serves as a transport network for deoxygenated blood from the heart to the lungs and then returns oxygen-rich blood back to the heart.
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
The process begins with the right ventricle of the heart pumping deoxygenated blood into the pulmonary trunk. This large vessel extends about 5 centimeters before splitting into the left and right pulmonary arteries. These arteries...
3.0K
Cranial Bones: Superior and Posterior View
5.1K
The superior view of the cranium shows the frontal and paired parietal bones.
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
5.1K
Nephrotic Syndrome I : Introduction
609
Nephrotic Syndrome is a chronic kidney disorder defined by clinical findings such as severe proteinuria, hypoalbuminemia, hyperlipidemia, and edema. These symptoms result from damage to the glomeruli, the kidney’s filtering units, increasing their permeability to proteins.Definition and Meaning:Proteinuria, defined as the loss of more than 3.5 grams of protein per day in adults, is a crucial feature of nephrotic syndrome. This condition is often accompanied by edema, the accumulation of...
609
Regulation of Stroke Volume
5.1K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
5.1K


