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Updated: Jan 29, 2026

Engineering Cell-permeable Protein
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Engineering Cell-permeable Protein

Published on: December 28, 2009

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工程VPg saRNA实现了在体内治疗性蛋白质的独立,低免疫性和精确编码

Zunyong Feng1, Liuxi Chu1,2, Qiang Li3,4

  • 1State Key Laboratory of Macromolecular Drugs and Large-scale Preparation, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou, China.

Nature communications
|January 27, 2026
PubMed
概括

使用病毒蛋白基因组链接 (VPg) 系统设计的自我放大mRNA (saRNA) 载体显示出改善的治疗潜力. 这种新的VPg saRNA方法克服了当前针对各种疾病的mRNA疗法的局限性.

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