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Updated: Jan 29, 2026

Malachite Green Assay for the Discovery of Heat-Shock Protein 90 Inhibitors
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人工智能和实验融合:一个协同途径,以发现JAK2抑制剂的发现

Maryam1, Hwangeui Cho2, Ankit Pokhrel1

  • 1Department of Electronics and Information Engineering, Jeonbuk National University, Jeonju, 54896, Republic of Korea.

Acta pharmacologica Sinica
|January 27, 2026
PubMed
概括

研究人员开发了一个CatBoost机器学习模型,使用分子描述符来识别强大的Janus激酶2 (JAK2) 抑制剂. 这种人工智能驱动的方法成功选了化学数据库,从而发现了具有潜在治疗应用的四种具有显著抑制活性的化合物.

关键词:
亚努斯酶2的作用是雅努斯酶抑制剂的使用人工智能的人工智能是人工智能.发现药物的发现.实验设计实验设计

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