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Updated: Jan 29, 2026

Assays for Validating Histone Acetyltransferase Inhibitors
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Assays for Validating Histone Acetyltransferase Inhibitors

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在LUAD和LUSC中,通过基因素脱乙酶抑制剂SAHA的差异转录组学调制

Fei Wang1, Qingjun Yang1, Lei Shu1

  • 1The Affiliated Panyu Central Hospital, Guangzhou Women and Children's Medical Center, Infection Medicine Research Institute of Panyu District, School of Biomedical Engineering, Guangdong University of Technology, The Fifth Affiliated Hospital, Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology, the NMPA and State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, 511436, China.

Clinical epigenetics
|January 28, 2026
PubMed
概括

像SAHA这样的歇斯顿脱乙酶抑制剂 (HDACi) 在非小细胞肺癌 (NSCLC) 亚型中表现出不同的反应. 萨哈在肺腺癌 (LUAD) 和肺状癌 (LUSC) 中使用不同的基因模块,提供针对亚型的治疗策略.

关键词:
HDAC 抑制剂的使用在NSCLCLC中,我们可以看到.个性化治疗是个性化的治疗.萨哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈哈转录基因模块化转录基因模块化

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