在外科病房使用抗生素:基于世卫组织AWaRe方法的点患病率调查
Jacopo Dolcini1,2, Giorgia Maria Ricciotti1, Giorgio Firmani1
1Department of Biomedical Sciences and Public Health, Section of Hygiene, Preventive Medicine and Public Health, Polytechnic University of the Marche Region, 60126 Ancona, Italy.
Antibiotics (Basel, Switzerland)
|January 28, 2026
概括
这项研究评估了在外科抗生素预防 (SAP) 中使用抗生素的使用情况,使用世界卫生组织 (WHO) 的访问,观察和储备 (AWaRe) 类和定义的每日剂量 (DDD). 结果显示主要是获取抗生素,与管理目标保持一致,并为质量改进提供见解.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 目前的手术抗生素预防 (SAP) 报告往往缺乏与世界卫生组织 (WHO) 访问,观察和储备 (AWaRe) 类和标准化体积指标的整合.
- 评估抗生素利用需要全面的数据,包括处方数和定义的每日剂量 (DDD).
研究的目的:
- 通过使用处方计数和DDD来评估意大利一家教学医院的SAP抗生素使用率.
- 在外科专科之间绘制WHO AWaRe类的地图,以确定管理特异性的差异.
主要方法:
- 从3月到5月2023年在手术患者中对SAP进行前性全医院监测.
- 使用2023年世卫组织AWaRe框架对SAP处方的分类.
- 通过世卫组织ATC/DDD方法量化抗生素消耗.
主要成果:
- 在拥有完整数据的793名患者中,分析了433份SAP处方.
- 塞法索林是最常见的药物 (82%).
- 93%的SAP处方和87.8%的DDD是WHO访问代理;7%的处方和12.2%的DDD是Watch代理;没有使用备用代理.
结论:
- 将AWaRe类与DDD和专业特定数据相结合,为SAP基准测试提供了一个强大的框架.
- 访问代理商的高比例与抗菌药物管理目标保持一致.
- 跨专业的变化突出了SAP中有针对性的质量改进举措的机会.
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