由于术后炎症反应导致的左心室附属物关闭装置中的错误阳性PET吸收
Marta Hernández-Meneses1, Guillermo Cuervo1,2, Marta Tormo-Ratera3
1Infectious Diseases Department, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, 08036 Barcelona, Spain.
Diagnostics (Basel, Switzerland)
|January 28, 2026
概括
在左心房尾关闭装置 (LAACD) 中,正子发射断层扫描 (PET) 的吸收是常见的,可能反映的是无菌炎症,而不是感染. 识别这种模式可以防止心血管感染诊断中的错误阳性.
科学领域:
- 心血管成像 - 心血管成像
- 核医学就是核医学.
- 医疗器械 医疗器械
背景情况:
- 阳位子发射断层扫描 (PET) 对于诊断心血管感染至关重要.
- 非传染性炎症过程可能导致假阳性PET结果.
- 左心房附属物关闭装置 (LAACD) 由于潜在的辐射追踪器吸收,存在诊断挑战.
研究的目的:
- 为了分析LAACD (AtriClip®) 中的放射追踪器吸收.
- 为了确定吸收是否与传染性或炎症过程有关.
- 为了防止对心血管感染的PET/CT扫描进行误解.
主要方法:
- 对28次PET/CT扫描 (20名患者) 具有植入LAACD的回顾性分析.
- 使用了18F-氧葡萄糖 (FDG) 和18F-胆 (CHO) 放射标记物.
- 审查了临床,实验室和成像数据,并对感染进行了长期随访.
主要成果:
- 在93%的研究中,在LAACD中观察到均的PET吸收,不论是标记物或植入以来的时间.
- 在任何病人身上都没有发现与设备相关的感染的证据.
- 在PET指示组之间或在患有/没有其他感染的患者中,SUV比率没有显著差异.
结论:
- 在LAACD中吸收FDG和CHO是一个一致的发现.
- 吸收可能代表无菌的,术后炎症反应,而不是真正的感染.
- 识别这种模式对于避免心血管感染评估中假阳性PET/CT结果至关重要.
相关概念视频
Inflammatory Response
16.6K
An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
16.6K
Inflammatory Response II: Inflammatory Exudate and Tissue Repair
7.7K
The immune system's inflammatory response destroys the invading pathogen, permitting the tissue to heal. The changes during the cellular and vascular stages allow exudate formation at the site of inflammation. The inflammatory exudate released from the wound has high protein content and a specific gravity above 1.020.
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
The typical wound exudate is odorless, transparent, straw-colored, thin, and watery. Exudate, however, can differ depending on the state of wound healing. Likewise, the...
7.7K
Inflammatory Response I: Vascular and Cellular
16.3K
The inflammatory response is the body's defense against infection, injury, or irritation from bacteria, trauma, toxins, or heat. Inflammation helps locate and destroy pathogens and remove damaged tissue elements to heal the body. During this initial phase, fluid, blood products, and nutrients migrate to the injured area, resulting in redness, heat, swelling, ache, and loss of function. Moreover, signs of systemic inflammation include fever, increased WBC count, malaise, anorexia, nausea,...
16.3K
False Memories
464
False memories represent a cognitive distortion in which individuals recall events that did not happen, or remember them in an altered form. This phenomenon highlights the brain's constructive nature in processing and recalling memories, emphasizing that memory is not a perfect representation of past events but rather a dynamic reconstruction influenced by various factors.
One primary source of false memories is misattribution, where individuals incorrectly associate external information...
One primary source of false memories is misattribution, where individuals incorrectly associate external information...
464
Surface Appendages of Archaea
650
Archaeal surface appendages are highly specialized structures essential for environmental adaptation, encompassing roles in adhesion, biofilm formation, and motility. Among these appendages, pili and archaella stand out for their distinct morphologies and functionalities, enabling archaea to thrive in diverse and often extreme environments.Pili: Adhesion and Biofilm FormationPili are filamentous structures assembled from pilin protein subunits, primarily contributing to adhesion and biofilm...
650
Design Example: Identifying the Locations of Monuments in the Field Using Global Positioning System Device
409
Surveyors use Global Positioning System (GPS) technology to measure the precise location and elevation of points on Earth. In a recent survey, GPS receivers were used to determine the coordinates and elevations of two park monuments. The process involved careful mission planning, data collection, and correction to ensure accuracy. The survey began with mission planning to identify optimal satellite visibility and minimize Position Dilution of Precision (PDOP). A geodetic control point...
409


