多焦点性和双边性的临床影响在乳腺甲状腺小癌中的淋巴结转移
Merima Goran1,2, Marko Buta1,2, Srdjan Nikolic1,2
1School of Medicine, University of Belgrade, Dr Subotica 8, 11000 Belgrade, Serbia.
Diagnostics (Basel, Switzerland)
|January 28, 2026
概括
乳头甲状腺小癌 (PTMC) 的多焦点性与更具侵略性的特征和更高的淋巴结转移率有关. 双边性可能表明更具侵略性的瘤,但不能独立预测转移.
科学领域:
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
- 手术病理学手术病理学
背景情况:
- 乳头甲状腺小瘤 (PTMC) 经常表现出多焦点和双边性.
- 关于宫淋巴结转移 (LNMs) 的这些特征的临床意义正在争论中.
研究的目的:
- 研究PTMC中的多焦点性和双边性模式.
- 确定这些模式与中央和侧部淋巴结转移的关联.
主要方法:
- 对254名经组织学确认的PTMC患者进行了回顾性分析.
- 患者接受了全甲状腺切除术,并进行中部和/或侧部部解剖.
- 统计分析评估了瘤特征和LNMs之间的关联.
主要成果:
- 多焦点瘤 (40.55%) 和双侧瘤 (27.17%) 是常见的.
- 多焦点与男性性别相关,囊入侵,较大的瘤大小和LNM增加.
- 更高的瘤焦点数量强烈预测了中部和侧面的NLM.
结论:
- 多焦点,特别是多焦点,是积极的PTMC特征和LNM的重要预测因素.
- 双边性表明更具侵略性的表型,但不是LNM的独立预测因素.
- 这些发现强调了风险分层,并为PTMC的手术/后续策略提供了信息.
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