作为可逆的前额网络损伤的巨型右翼脑膜瘤:一个伪bvFTD病例,带有静脉节约性骨基切除
Valentin Titus Grigorean1,2, Octavian Munteanu1,3, Felix-Mircea Brehar1,4
1Faculty of General Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Diagnostics (Basel, Switzerland)
|January 28, 2026
概括
巨型状翼脑膜瘤可以模仿痴呆症. 通过成像和测试的早期识别可以导致手术治疗和症状的逆转,突出显示它们的性质是可治疗的网络病变.
科学领域:
- 神经科学是一个神经科学.
- 神经外科 神经外科
- 在瘤学瘤学.
背景情况:
- 巨型状翼脑膜瘤可以呈现为头骨底部质量.
- 这些瘤可以压缩额头通路,导致dysexecutive-无情综合征.
- 这种综合征可能被误认为是原发性神经退行性疾病.
研究的目的:
- 为了说明床边表型和多式成像如何识别手术可治疗的网络病变.
- 为了证明巨型状翼脑膜瘤可以导致伪退行性额头综合征.
- 突出通过适当的手术干预来扭转这些综合征的潜力.
主要方法:
- 一个老年女性的案例介绍,她的执行功能和冷漠度下降了两年.
- 标准化的神经心理评估显示了基于前部的执行特征.
- 磁共振成像 (MRI) 显示一个大,右前--基底外轴瘤与相关的血管性胀和中线转移.
- 使用带有 devascularization, debulking 和静脉保存的 pterional 切除术 (辛普森一级切除) 的手术切除.
主要成果:
- 该患者出现了模仿行为变异前性痴呆症 (bvFTD) 的症状.
- 手术切除导致执行功能和整体功能的连续改善.
- 术后成像证实了持续的减压和对称心室,与临床康复相关.
结论:
- 非主导的状翼脑膜瘤可以导致可逆的伪退行性额头综合征.
- 识别为网络病变和量身定制的,静脉节约的头骨基底手术对于成功治疗至关重要.
- 对比增强成像和正面检测对于识别可接受手术的非典型痴呆症呈现有价值.
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