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Updated: Jan 29, 2026

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BDNF和血清素通路的系统相互作用定义了对中脑5-HT7过度表达和慢性乙醇消费的行为和分子反应

Alexander Rodnyy1, Alina Oreshko1, Dmitry Eremin1

  • 1Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Science, Novosibirsk 630090, Russia.

Biomolecules
|January 28, 2026
PubMed
概括

长期暴露于乙醇会改变大脑中的血清素 (5-HT) 和BDNF信号,影响酒精使用障碍 (AUD) 的行为. 神经适应是特定于区域和水平的,而不是全球性的反应.

关键词:
5-HT7受体的受体是什么?由AAV介导的过度表达.大脑衍生神经营养因子 (BDNF)大脑的5-HT系统.慢性酒精饮料的使用.雄性小鼠 雄性小鼠

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