在溶液中用β发射体Lu-1777进行辐射后,外周血液单核细胞中的染色体纳米组织

Myriam Schäfer1, Razan Muhtadi2, Sarah Schumann3

  • 1Kirchhoff-Institute for Physics, Heidelberg University, Im Neuenheimer Feld 227, 69120 Heidelberg, Germany.

Biomolecules
|January 28, 2026
PubMed
概括

低剂量的贝塔辐射从Lutetium-177诱导DNA双链断裂 (DSBs) 和相关的修复蛋白,显示近距离与异色染色素标记. 这表明DSBs可能不会放松异色素蛋白,影响核医学治疗中的DNA修复.

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