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Updated: Jan 29, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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开发针对线粒体的PARP抑制剂

Pavels Dimitrijevs1, Marina Makrecka-Kuka1, Pavel Arsenyan1

  • 1Latvian Institute of Organic Synthesis, Aizkraukles 21, LV1006 Riga, Latvia.

Biomolecules
|January 28, 2026
PubMed
概括

研究人员通过将现有药物与合物开发出针对线粒体的新型PARP抑制剂. 这些新化合物对缺乏BRCA1的乳腺癌细胞具有增强的功效,同时保持选择性.

关键词:
在 PARP 抑制剂.结合心脏脂素的结合线粒体向的目标是线粒体这就是Olaparib.酸的合物是一种合物.卢卡卡里布是什么意思

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