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偏头痛是非关节炎前侧缺血光学神经病变的危险因素吗? 来自国家病例控制研究的见解

Itamar Ben Shitrit^1,2, Eyal Walter^3,4, Erel Domany⁵

¹Joyce & Irving Goldman Medical School, Ben-Gurion University of the Negev, Be'er-Sheva 84101, Israel.

|January 28, 2026

概括

偏头痛没有增加非动脉炎前面缺血性视觉神经病变 (NAION) 的风险,但患有偏头痛的女性更早发展了NAION. 患有NAION的偏头痛患者中,充血性心力衰竭更常见,这表明低输液可能起作用.

科学领域:

眼科医生眼科眼科
神经学神经学
血管医学血管医学

背景情况:

偏头痛与脑血管风险增加有关.
偏头痛和非动脉炎前部缺血性视神经病变 (NAION) 之间的联系尚未得到充分证实.
了解这种关联可以为风险分层和风险管理提供信息.

研究的目的:

为了调查偏头痛和NAION之间的关联.
为了比较患有和没有偏头痛病史的患者中NAION的患病率和临床特征.
确定影响偏头痛患者NAION发作的因素.

主要方法:

使用基于人口的电子病历进行回顾性病例控制研究.
对NAION病例 (n=1629) 与倾向性得分匹配的对照组 (n=6433) 的比较.
分析偏头痛的患病率,临床特征和并发症.

主要成果:

在NAION患者和对照组中,偏头痛的患病率相似 (3.8%对3.3%).
患有NAION的偏头痛患者更年轻,糖尿病和外周血管疾病的发病率更低.
患有偏头痛的女性在不患偏头痛的女性 (60岁与69岁) 相比,在显著更年轻的年龄发展出NAION.
在患有NAION的偏头痛患者中,充血性心力衰竭更为普遍 (9.7%对2.4%).
偏头痛独立地与NAION发病时的年轻年龄有关,特别是在59岁以下的患者中.

结论:

偏头痛与NAION的更高患病率没有关联.
女性偏头痛患者在较早的年龄和较少的血管并发性疾病中经历NAION.
患有NAION的偏头痛患者中充血性心力衰竭的患病率增加表明系统性低输血可能起作用.

关键词:

大脑自我调节充血性心力衰竭是一种偏头痛偏头痛偏头痛偏头痛没有动脉炎的前面缺血光学神经病变.眼睛动脉的眼动脉.

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