能量密集的高脂肪/高糖饮食诱导BALB/c小鼠的2型糖尿病,没有遗传修饰和化学剂

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Alma Nelly Diaz-Herreros1,2, Amaranta Sarai Valdez-Guerrero3, Juan Carlos Cancino-Díaz4

  • 1Laboratorio de Inmunología Aplicada, Departamento de Inmunología, Escuela Nacional de Ciencias Biológicas del Instituto Politécnico Nacional, Prolongación de Carpio y Plan de Ayala s/n, Col. Santo Tomas, Delg. Miguel Hidalgo, Mexico City 11340, Mexico.

Biology
|January 28, 2026
PubMed
概括

高热量饮食 (HCD) 可以在BALB/c小鼠中诱导2型糖尿病 (T2DM),这种模型以前对这种疾病有抵抗力. 这一发现允许在没有遗传修饰的情况下对糖尿病易感性进行新的研究.

关键词:
在BALB/c小鼠中.在C57BL/6小鼠.动物模型动物模型高卡路里饮食高卡路里饮食.2型糖尿病是什么?

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