应用特定的测量不确定性软件用于测量水生产品中的恩罗夫洛克萨残留物,使用快速定量 (QQ) 方法
Bo Rong1,2,3,4,5, Haitao Zhang6, Wenjing He2
1School of Marine Technology and Environment, Dalian Ocean University, Dalian 116023, China.
Biology
|January 28, 2026
概括
一个新的移动应用程序,AquaUncertainty Pal,通过整合实时测量不确定性计算,提高快速定量免疫检测的可靠性,以检测水产养殖中的恩罗夫洛克萨和西普罗夫洛克萨残留物.
科学领域:
- 食品科学 食品科学 食品科学
- 分析化学 分析化学
- 环境科学 环境科学
背景情况:
- 快速定量 (QQ) 免疫试验被广泛用于水产养殖中的恩洛夫洛克萨 (ENR) 和西普洛克萨 (CIP) 残留物分析.
- 质量质量方法的数量可靠性有限的原因在于,在实地测试中很少考虑测量不确定性 (MU).
研究的目的:
- 开发一个移动应用程序,AquaUncertainty Pal,用于QQ工作流中的实时MU计算.
- 提高水产养殖残留分析的计量可靠性和准确性.
主要方法:
- 开发一个移动应用程序,将实时MU计算集成到QQ免疫试验中.
- 软件自动评估采样和管道的不确定性来源,可视化不确定性预算,并指导用户.
- 根据ISO/IEC 17025认证的LC-MS/MS进行验证,并与20名技术人员进行了用户研究.
主要成果:
- 集成的软件提高了管管的精度 (100微升的RSD从4.1%提高到1.79%).
- 减少了52%的运营商间变化 (CV).
- 在最大残留量 (MRL) 附近,符合性评估的准确性从25%提高到70%.
结论:
- 实时MU可视化有效地引导技术人员实现一致的管道和解释.
- 将MU集成到QQ工作流中是可行的,并且有效地提高了残留物分析的可靠性.
- 数字框架支持在水产养殖中基于不确定性的残留物监测.
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