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由内分泌干扰剂引起的生殖毒性的应用在罗提弗:一篇评论

Guangyan Liang¹, Shenyu Liu¹, Shan Wang¹

¹College of Marine Science and Technology and Environment, Dalian Ocean University, Dalian 116023, China.

|January 28, 2026

概括

破坏内分泌的化学物质损害了鱼的繁殖,影响了水产养殖和生态系统. 研究缺陷包括长期影响和跨代毒性.

科学领域:

环境毒理学环境毒理学
水生生态学水生生态学
生殖生物学生殖生物学

背景情况:

内分泌干扰化学物质 (EDC) 污染水生环境,破坏生物体内分泌功能,威胁生态系统的稳定性.
罗提弗在水产养殖中是重要的活料,使其生殖健康对海洋鱼类,和幼虫的生产至关重要.
由于EDC引起的鱼的生殖能力受损,对海洋生态系统和水产养殖的可持续性产生了连锁影响.

研究的目的:

综合当前关于EDC在鸟中的生殖毒性知识.
确定这一领域的关键发现,后果和研究缺口.
支持EDC风险评估,并为未来的研究优先事项提供信息.

主要方法:

符合PRISMA的系统文献审查.
对传统和新兴EDC (重金属,PFAS,,酸盐,PBDE,荷尔蒙,消毒副产品,微塑料,制药代谢物) 的研究进行分析.
评价 rotifer 特定物种和暴露时间的敏感性.

主要成果:

不同的EDC会造成明显的生殖损害,包括极度毒性 (Hg2+),卵巢损伤 (BDE-47) 和跨代影响 (微塑料,4-nonylphenol).
罗提弗的敏感性因物种和暴露时间而异 (例如,BDE-47 LC50值在24小时和96小时暴露之间有很大差异).
氧化应激是一种常见的机制;联合EDC暴露可以产生协同作用或对抗作用,减少人口密度和改变食物网动态.

结论:

暴露于EDC对鱼种群构成重大威胁,通过降低生殖能力和跨代毒性影响水产养殖和生物多样性.
仍然存在关键的研究缺口,特别是关于长期,低度暴露,跨代毒性机制,EDC-微生物群相互作用以及 PFAS 等新兴污染物的毒性.
解决这些缺陷对于准确的EDC风险评估和保护水生生态系统和可持续水产养殖至关重要.

关键词:

破坏内分泌的化学物质破坏内分泌的化学物质生殖性毒性生殖性毒性罗蒂菲尔斯 (Rotifers) 是一种小鸟类.灵敏度灵敏度灵敏度灵敏度灵敏度

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