在下癌中进行三维手术规划:十年的临床经验和结果
Li H Yang1, Bram B J Merema1,2, Joep Kraeima1,2
1Department of Oral & Maxillofacial Surgery, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9700 RB Groningen, The Netherlands.
Cancers
|January 28, 2026
概括
在下口腔状细胞癌 (OSCC) 中,三维虚拟手术规划 (3D-VSP) 在瘤切除和重建方面显示出高精度. 优化护理途径间隔和减少并发症是改善瘤治疗结果的关键.
科学领域:
- 在瘤学瘤学.
- 手术规划 手术规划
- 医疗成像医学成像
背景情况:
- 三维虚拟手术规划 (3D-VSP) 是下口腔状细胞癌 (OSCC) 的标准.
- 指南建议最长30天的护理途径间隔 (CPI) 和5毫米的自由骨边缘.
- 合并的MRI和CT数据可以为3D-VSP准确地划分瘤.
研究的目的:
- 在下骨OSCC中评估骨边缘和CPI指南的遵守.
- 使用3D-VSP.评估瘤切除和重建的准确性.
- 将3D计划下重建的并发症与不同的骨质合成板进行比较.
主要方法:
- 对接受细分下切除术 (2014-2024) 的患者的回顾性分析.
- 对CPI,临床结果和并发症的分析.
- 术前虚拟计划与术后结果的比较,以评估准确性.
主要成果:
- 中位数CPI为34天;93.7%的骨边缘没有瘤.
- 平均绝对切除偏差为1.63毫米 (±1.42).
- 患者特异性植入物 (PSI) 重建比传统的板块更准确,但显示了更多的板块暴露.
结论:
- 3D-VSP在下OSCC切除和重建中实现了高精度,具有有利的骨边缘.
- 缩短CPI和最大限度地减少生物并发症对于改善瘤结果至关重要.
- 需要进一步的研究来优化3D-VSP的临床使用并减少并发症.
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