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在大动脉和心血管研究中模拟循环应用的现状:一个范围审查

Felix E N Osinga^1,2, Nesar A Hasami^1,3,4, Jasper F de Kort^1,4

¹Section of Vascular Surgery, Cardio Thoracic Vascular Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, 20122 Milan, Italy.

|January 28, 2026

概括

假循环循环 (MCLs) 是用于大动脉研究的多功能桌面工具,模拟心血管条件用于生物力学,血液动力学和设备测试. 需要标准化报告以提高可复制性和临床翻译性.

科学领域:

生物医学工程生物医学工程
心血管研究研究心血管研究
医疗模拟医疗模拟

背景情况:

假循环循环 (MCLs) 提供了对人类心血管系统的受控基板模拟.
它们为血液动力学和生理学研究提供了安全和可重复的环境.
本综述侧重于MCL在大动脉模拟中的当前应用.

研究的目的:

系统地绘制用于大动脉模拟的MCL景观.
确定MCL在心血管研究中的主要应用领域.
综合有关MCL配置,大动脉模型和研究目标的数据.

主要方法:

在PubMed,Scopus和Web of Science进行了系统的文献搜索.
符合条件的研究被分类为主题:生物力学,血液动力学,设备测试,诊断和培训.
数据合成涉及对研究目标,MCL设置和使用的大动脉模型的叙事审查.

主要成果:

84项研究符合纳入标准,具有多样化的应用.
关键的研究领域包括大动脉生物力学 (25项研究),血液动力学 (23项研究) 和设备测试 (22项研究).
大动脉模型各不相同,包括生物组织 (猪,尸体) 和3D打印的幻影 (55项研究).

结论:

MCLs是研究大动脉病理生理学和内血管治疗的多功能临床前平台.
应用范围从生物力学表征到设备性能评估.
标准化报告对于提高MCL研究的可复制性和加速临床翻译至关重要.

关键词:

德瓦尔 (TEVAR) 是一个大动脉的动脉.大动脉硬性大动脉硬血管内大动脉修复模拟的循环循环循环循环.脉冲波的速度是脉冲波的速度.

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