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Updated: Jan 29, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
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Published on: September 20, 2016

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低VAFTP53突变AML在单中心队列中显示出明显的生物学特征

Xiaoxuan Lu1, Xiaohang Ma1, Kainan Zhang1

  • 1Beijing Key Laboratory of Cell and Gene Therapy for Hematologic Malignancies, Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Peking University, Beijing 100044, China.

Biomedicines
|January 28, 2026
PubMed
概括

对TP53突变性急性髓性白血病 (AML) 的10%变异性等位基因频率 (VAF) 值具有临床相关性. 低VAFTP53突变AML可能是一个独特的生物亚组,预后不佳.

关键词:
在AML,AML就是AML.这种突变是TP53突变.低VAF的VAF可以使用.

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