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Updated: Jan 29, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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合理设计的双激酶抑制剂用于阻断性睡眠呼吸暂停的管理-一项计算研究

Kosi Gramatikoff1, Miroslav Stoykov2, Mario Milkov2

  • 1Research Institute, Medical University "Prof. Dr. Paraskev Stoyanov", 55 Marin Drinov Str., 9002 Varna, Bulgaria.

Biomedicines
|January 28, 2026
PubMed
概括

这项研究确定了CK1δ-PINK1信号通路作为阻塞性睡眠呼吸暂停 (OSA) 药物发现的关键目标. 新的双酶抑制剂被理性地设计,为OSA管理提供了一种新的精确治疗方法.

关键词:
尼吉拉·萨蒂瓦 (Nigella sativa) 是一种植物.标签:PINK1PINK1PINK1PINK1凯赛因激酶1三角酶 (CK1δ)这种疾病是共患的.双酶抑制剂 双酶抑制剂网络药理学 网络药理学神经退行症的神经退行症阻塞性睡眠呼吸暂停症是什么植物类化合物植物类化合物精密治疗疗法精确治疗疗法有理性的药物设计.

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