激光偏移声场量化:用于聚焦超声波场特征的非侵入性测量技术
Yang Xu1,2, Hongde Liu3, Yaoan Ma3
1Department of Biomedical Engineering, School of Life Science and Technology, and Advanced Biomedical Imaging Facility, Huazhong University of Science and Technology, Wuhan 430074, China.
Bioengineering (Basel, Switzerland)
|January 28, 2026
概括
一种新的非侵入性激光偏移声场量化 (LDAQ) 方法准确地测量高压聚焦超声波场. 该技术通过提供可靠的声场表征,提高了聚焦超声疗法的安全性和有效性.
科学领域:
- 声学 声学 在声学方面
- 生物医学工程 生物医学工程
- 光学物理学 光学物理学
背景情况:
- 聚焦超声波 (FU) 对于瘤切除和疼痛管理等临床应用至关重要.
- 准确的声场量化对于FU的安全性和有效性至关重要.
- 现有的测量方法有局限性,包括侵入性和无法测量高声压.
研究的目的:
- 开发和验证一种用于定量高压聚焦超声波场的非侵入性方法.
- 为了解决当前声学测量技术的局限性.
主要方法:
- 提出了基于激光偏移原理的非侵入性激光偏移声场量化 (LDAQ) 方法.
- 使用声光偏移,精确控制和同步触发构建了一个实验系统.
- 采用断层扫描,用于重建的变换,以及适应式加权聚变来映射光学信号到声压.
主要成果:
- 通过LDAQ技术,成功测量了FU传感器的声场.
- 重建后的结果显示,与水电声测量和数值模拟的结果具有很高的一致性.
- 实现了0.1102 (LDAQ与模拟) 和0.1422 (LDAQ与水电话) 的根平均平方误差.
结论:
- 通过LDAQ,可以进行非侵入性,高精度的量子测量,对Megapascal级别的聚焦声场进行定量.
- 这种方法为声场表征提供了一种可靠的方法.
- 支持FU治疗的优化和FU设备的标准化.
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