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量化CT和MRI的活体动脉变形:对细分,运动跟踪和动力学指标的系统审查
Rodrigo Valente1, Bernardo Henriques1, André Mourato1
1Research & Development Unit for Mechanical and Industrial Engineering (UNIDEMI), Department of Mechanical and Industrial Engineering, NOVA School of Science and Technology, NOVA University Lisbon, 2829-516 Caparica, Portugal.
Bioengineering (Basel, Switzerland)
|January 28, 2026
概括
使用CT和MRI量化人类动脉运动,揭示了与年龄相关的动脉应变和硬度增加的减少. 这些发现突出了衰老和疾病对血管动态的影响.
科学领域:
- 生物医学工程 生物医学工程
- 医疗成像医学成像
- 心血管研究研究心血管研究
背景情况:
- 精确量化人类动脉运动和变形对于了解血管健康至关重要.
- 计算机断层扫描 (CT) 和磁共振成像 (MRI) 为体内动脉分析提供了非侵入性方法.
研究的目的:
- 系统地审查和综合使用CT和MRI量化人类动脉的三维,时间解析 (3D+t) 变形和运动的方法.
- 识别常见的细分和运动跟踪技术以及衍生动力学指标.
主要方法:
- 在主要科学数据库中按照PRISMA指南进行系统的文献搜索.
- 包括体内,患者特定的CT或MRI研究来量化动脉运动或变形.
- 对35项选定的研究进行了定性分析和叙事综合.
主要成果:
- 主动轮和值是常见的细分方法;用于时间运动跟踪,使用voxel注册和表面方法.
- 衍生指标包括应变,伸展性,曲率和估计的墙壁度.
- 动脉应变随着年龄和疾病而降低;硬度与几何重塑相关;变形在空间上是异质的.
结论:
- 已建立的方法允许从医学成像中量化动脉变形和运动.
- 衰老和疾病显著影响动脉生物力学,减轻了应变和改变了硬度.
- 由于数据的局限性,需要进一步的研究来进行强大的交叉方法比较.
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