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Updated: Jan 29, 2026

Preparation and Characterization of SDF-1α-Chitosan-Dextran Sulfate Nanoparticles
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通过ASO载荷纳米粒子调节miR-485-3p/PGC-1α路径减轻ALS病原性

In Soo Ryu1, Dae-In Ha1, Yeon-Joo Jung1

  • 1BIORCHESTRA Co., Ltd., 1, Gukjegwahak 2-ro, Yuseong-gu, Daejeon 34000, Republic of Korea.

International journal of molecular sciences
|January 28, 2026
PubMed
概括

微RNA-485-3p在肌缩侧面硬化症 (ALS) 中升高. 用BMD-001S准这种微RNA改善了运动神经元功能,并减少了小鼠的疾病标志物.

关键词:
反感核酸 (ASO) 是一种反感核酸.这是一个微型RNA.纳米粒子是一种纳米粒子.神经退行性疾病是一种神经退行性疾病.神经炎症是一种神经炎症.

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