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Updated: Jan 29, 2026

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SUMOylation保护内皮细胞表达的白细胞特异蛋白1免受乌比基因化介导的蛋白质体退化,并促进其核出口

Mokarram Hossain1, Jiannan Huang1, Yang Su1

  • 1Department of Anatomy, Physiology and Pharmacology, College of Medicine, University of Saskatchewan, Saskatoon, SK S7N 5E5, Canada.

International journal of molecular sciences
|January 28, 2026
PubMed
概括

白细胞特异性蛋白1 (LSP1) 是SUMOylated,这种修饰对于其稳定性和内皮细胞的适当贩运至关重要. 这种SUMOylation可以防止蛋白质体的降解,并调节LSP1的活性.

关键词:
这就是SUMO1的意义.这就是SUMOylation的作用.细胞内膜的通透性白细胞特异蛋白 1 白细胞特异蛋白 1后翻译修改后的修改.

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