在初级单症状夜间尿尿失禁中长期复发的预测因素:一个回顾性队列研究
1Department of Pediatrics, Ümraniye Training and Research Hospital, University of Health Sciences, 34764 Ümraniye, Türkiye.
Children (Basel, Switzerland)
|January 28, 2026
概括
患有初级单症状夜间尿尿症 (PMNE) 的儿童的复发率很高,但以日记为基础的膀容量预测了长期缓解. 膀容量与估计膀容量比率超过79%表明PMNE患者复发风险较低.
科学领域:
- 儿科 儿科 儿科
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 儿童健康 儿童健康
背景情况:
- 晚间尿道是儿童在睡眠期间不自发的排尿.
- 主要单症状夜间尿尿症 (PMNE) 缺乏白天症状,诸如膀容量减少等因素有助于复发.
- 在PMNE中长期复发的预测因素仍然不清楚.
研究的目的:
- 确定患有初级单症状夜间尿尿症 (PMNE) 的儿童长期复发的预测因素.
- 为了比较基于日记与基于超声波的膀容量测量在预测PMNE复发中的有效性.
- 建立一个临床值来预测PMNE的持续缓解.
主要方法:
- 对227名患有PMNE实现缓解的儿童 (≥5岁) 的回顾性队列研究.
- 标准化为期3个月的治疗,随后进行评估,包括频率/体积 (F/V) 日记和尿液流量计 (UFM).
- 用湿夜日记进行一年的随访;使用比较统计和ROC分析分析复发预测因素.
主要成果:
- 48.5%的儿童在一年内复发.
- 基于日记的功能性膀容量 (FBC) 显著高于基于UFM的容量.
- 减少的日记FBC/估计膀容量 (EBC) 比率 (<79%) 与更高的复发率相关 (p <0.001).
结论:
- 从日记中获得的膀容量是长期PMNE复发的更强的预测因素,而不是基于UFM的评估.
- 基于日记的FBC/EBC比率>79%的平均值可以确定患有复发风险较低的儿童.
- 儿童日记能力较低可能需要更密切的监测或延长治疗.
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