预测NSTEMI中的对比诱导病:HALP评分的作用
Evliya Akdeniz1, Yasin Yüksel2, Cennet Yildiz1
1Department of Cardiology, Bakırköy Dr. Sadi Konuk Training and Research Hospital, 34147 İstanbul, Turkey.
Medicina (Kaunas, Lithuania)
|January 28, 2026
概括
哈尔普评分有效预测非ST段升高心肌梗塞 (NSTEMI) 患者进行冠状动脉手术的对比诱导性病 (CIN). 较低的HALP得分表明患有CIN的风险更高.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 生物标志物 生物标志物
背景情况:
- 对比诱导性病 (CIN) 是侵袭性冠状动脉手术后的一个重大风险.
- 反映营养和炎症状况的HALP得分可以预测CIN.
- 非ST段升高心肌梗塞 (NSTEMI) 患者在冠状动脉血管造影 (CAG) 或皮肤冠状动脉干预 (PCI) 后容易发生CIN.
研究的目的:
- 评估在接受CAG或PCI的NSTEMI患者中HALP得分和CIN发展之间的关联.
- 确定该患者队列中CIN的HALP得分的预测值.
主要方法:
- 对577名接受CAG或PCI的NSTEMI患者进行了回顾性研究.
- 根据CIN发育,患者被分类.
- 计算HALP得分并进行组间比较;执行多变量分析和ROC分析.
主要成果:
- 12.8%的患者发生了CIN.
- CIN患者年龄较大,糖尿病发病率较高,功能较差,血红蛋白,白蛋白和淋巴细胞水平较低.
- 在患有CIN的患者中,HALP得分显著较低 (15.88比53.86,p<0.001).
- HALP评分是CIN (OR:0.895,p < 0.001) 的独立逆预测指标,具有良好的预测准确性 (AUC:0.780).
结论:
- 哈尔普评分是一种简单,可访问和具有成本效益的生物标志物,用于预测NSTEMI患者的CIN.
- 较低的HALP得分与侵袭性冠状动脉手术后CIN风险增加有关.
- 哈尔普得分显示了强大的预测价值和CIN发展的准确性.
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