COVID-19 和间歇性肺部疾病
Roberto G Carbone1, Sharada Nagoti2, Assaf Monselise3
1Department of Internal Medicine, University of Genoa, 16132 Genoa, Italy.
Medicina (Kaunas, Lithuania)
|January 28, 2026
概括
间歇性肺病 (ILD) 是COVID-19的主要长期并发症,导致肺纤维化和功能减弱. 管理正在发展,正在研究更好的诊断和治疗这种慢性疾病的方法.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 病理学 病理学 病理学
背景情况:
- 由SARS-CoV-2引起的COVID-19可能导致严重的并发症.
- 间歇性肺病 (ILD) 是一个显著的长期后果,其特点是渐进的肺纤维化和呼吸功能受损.
研究的目的:
- 为 COVID-19 后的 ILD 提供一个更新的叙事审查.
- 从2020-2025年开始,审查研究出版物和临床指导方针.
主要方法:
- 诊断包括病史,生理检查,肺功能测试和成像 (HRCT).
- 肺活检 (低温活检或VATS) 可以用于组织学确认.
主要成果:
- 后COVID-19ILD呈现为一种慢性疾病,具有持续的呼吸道症状,放射学发现和肺功能减弱.
- 危险因素包括严重的急性疾病,晚年,男性性别和吸烟. 预后有所不同,一些患者的病情有所改善,而另一些患者的病情则有所下降.
- 目前的治疗方法包括皮质类固醇,抗纤维素药物 (例如,内兰多米拉斯),氧气支持,肺部康复,戒烟和疫苗接种.
结论:
- ILD是COVID-19的一个显著的长期并发症.
- 需要进一步的研究来阐明病理生理学和优化临床管理.
- 预计会出现新的诊断和治疗策略.
相关概念视频
Lung Capacity
56.2K
The air in the lungs is measured in volumes and capacities. Lung volume measures reflect the amount of air taken in, released, or left over after a lung function, like a single inhalation. Lung capacity measures are sums of two or more lung volume measures.
56.2K
Other Nuclides: 31P, 19F, 15N NMR
777
Many organic, inorganic, and biological molecules contain spin-half nuclei such as nitrogen-15, fluorine-19, and phosphorus-31. As a result, NMR studies of these nuclei have found extensive applications in chemical and biological research.
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...
While fluorine-19 and phosphorous-31 have high natural abundances (100%) and positive gyromagnetic ratios, nitrogen-15 has a low natural abundance and a negative gyromagnetic ratio. However, nitrogen-15 is still preferred over nitrogen-14 (which has a...
777
Pleura of the Lungs
7.1K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
7.1K
Inflammatory Bowel Disease II: Crohn's Disease
1.0K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.0K
Gross Anatomy of the Lungs
4.7K
The lungs are a pair of vital organs connected to the trachea via the left and right bronchi. The base of these organs meets the dome-shaped muscle known as the diaphragm. Encased by the pleurae, the lungs contact the mediastinum. The right lung is shorter yet wider, and has a larger volume than the left lung. The left lung has an indentation known as the cardiac notch. The superior region of the lungs is referred to as the apex, whereas the base is the lower region near the diaphragm. The...
4.7K
Immunodeficiency Diseases
2.3K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
There are three main causes of immunodeficiency...
2.3K


