大脑转移的时间动态和异质性:对当前MRI监测实践中的脆弱性进行单一中心的回顾性分析
Claudia Tocilă-Mătășel1,2, Sorin Marian Dudea1, Gheorghe Iana2
1Department of Radiology, Faculty of Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.
Medicina (Kaunas, Lithuania)
|January 28, 2026
概括
常规的MRI报告往往无法追踪随时间推移的大脑转移,特别是在复杂或多波疾病中. 这种碎片化阻碍了准确的疾病演变评估,这表明需要在随访中改善病变连续性.
科学领域:
- 神经瘤学神经瘤学
- 放射学 放射学是一门学科.
- 医学成像分析 医学成像分析
背景情况:
- 大脑转移通常在长期存活的患者中表现出多波进化.
- 当前的临床实践往往由于对对进行的MRI比较而导致损伤水平的连续性碎片化.
研究的目的:
- 评估标准叙述性MRI随访报告在维持纵向病变身份方面的能力.
- 评估从例行报告中重建连贯的疾病演变轨迹.
主要方法:
- 追溯观察性研究,对731名脑部MRI检查 (73名患者) 进行了至少三次扫描.
- 一位神经放射学家进行了纵向病变跟踪,并将报告一致性与参考标准进行了比较.
- 损伤身份保护的评估是基于报告中跨时间点的明确联系.
主要成果:
- 超过一半的监测病变在报告中被遗漏或成为治疗后的后果.
- 报告一致性随着疾病复杂性的增加而下降:统一进化为60%,混合进化为18.2%.
- 随着连续的转移性波浪,损伤身份的保存显著下降 (1波的65.2%,为3波的18.2%).
结论:
- 常规的MRI报告对于简单,均的大脑转移病例是充足的,但在复杂,异质或多波疾病中失去了关键细节.
- 目前的文档提供了碎片化的快照,而不是疾病进展的综合纵向视角.
- 需要通过人工智能工具增强损伤水平的连续性,以提高MRI监测准确性和大脑转移的临床实用性.
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